NMNH is the reduced state of β-nicotinamide mononucleotide (NMN), which is one of the NAD+ (coenzyme I) precursors. NAD+, one of the most important biomolecules in cells, is present in all life forms. As a coenzyme, it participates in various redox reactions and regulates a variety of biological processes to combat disease, such as energy metabolism, protein translation and modification, DNA repair, cellular stress, regulation of gene expression, and cellular signaling. Relative to NMN, NMNH shows a significant role in boosting NAD+ level.
Quickly enhance in vitro NAD+
β-Nicotinamide mononucleotide Reduced not only significantly increases the level of NAD+in cells, but also accelerates the rate of increase in NAD+concentration.
NMNH acts as an effective NAD+enhancer in vitro.
NMNH Powder can increase the NAD+content in these cells and is more effective than NMN at the same concentration.
Increase NAD+concentration in the body
98% NMNH Powder can effectively increase the concentration of NAD+in the blood, and can quickly increase NAD+levels within 1 hour after supplementation, which is much higher than NMN. It is worth noting that after supplementing with NMN, the NAD+content in the blood drops to the basic level after 4 hours, but NMNH can maintain a more than 2-fold increase in NAD+concentration within 20 hours after the first injection. Compared with NMN, NMNH can enhance NAD+levels in various tissues, with the liver (5-fold increase) and kidneys (2-fold increase) having the greatest impact. Surprisingly, NMNH also significantly increased the content of NAD+in brain, gastrocnemius muscle muscle, brown adipose tissue tissue and heart, which NMN could not do.
Repair of tubular epithelial cells
NAD+homeostasis is crucial for repairing damaged epithelial cells and maintaining cell biological activity. Supplementing the same concentration of NMNH and NMN can increase the concentration of NAD+by 5-fold and 2-fold, respectively; In hypoxic/reoxygenated environments, NMNH and NMN can increase higher NAD+concentrations. After analysis, supplementing NMNH can reduce cell damage during hypoxia/reoxygenation injury, and enhance cell repair ability by targeting NAD+regeneration, enhancing mitochondrial activity, and nucleotide metabolism.
Inhibiting cell growth
It was found that NMNH can enhance the accumulation of intracellular NADH, inhibit cell glycolysis and tricarboxylic acid cycle (TCA cycle), and inhibit cell growth, while NMN can only limited inhibit cell glycolysis.
Repress aging
·Mitigate inflammation
·Enhance energy metabolism
·Improve immune cell function
·Increase insulin sensitivity
·Reduce the risk of dyslipidemia
·Boosting the NAD(H) level in cells and tissues
·The inhibitory roles of NMNH in glycolysis, TCA cycle and cell growth
·Improve mitochondrial function
·Regulate DNA repair and gene expression
·Alleviate hypoxia/reoxygenation-induced injury in (renal tubular epithelial) cells and facilitate the healing
Cosmetic
It was found that NMNH can enhance the accumulation of intracellular NADH, inhibit cell glycolysis and tricarboxylic acid cycle (TCA cycle), and inhibit cell growth, while NMN can only limited inhibit cell glycolysis.
Health product
This dietary supplement contains of NMNH per serving to help boost NAD+ levels in the body.
Animal healthcare
High purity —— up to 98%
·Self-owned factory —— The first to realize mass production of NMNH worldwide
·Top technology platform for bioenzyme catalytic synthesis
·Exclusive R&D team of Masters and PhDs —— Wisdom as the engine to drive innovation
·Multiple choice to meet diverse needs:（△Lyophilized Powder/ △Crystallized Powder/ △Amorphous △Eutectic）
·Quality assurance: Experiment verification (△Enzymatic assay; △QNMR; △Stability test )
Shaanxi Rebecca Bio-Tech adheres to strict quality control measures throughout the production process. Our advanced testing facilities ensure that all products, including our powder, meet international quality standards. We carry out regular inspections, including:
Raw material quality checks
In-process testing
Final product testing
For powder products, we usually send the products together with cartons or fiber drums.For liquid products, we usually send the product together with a plastic.
Our packaging methods are 1 kg/aluminum bag, 25 kg/box, and 25 kg/barrel. For some products that require special packaging during transportation, we will carry out more detailed packaging.
We support shipping by air, sea, FedEx, DHL, TNT, EMS, UPS, SF, and other carrier.
At Shaanxi Rebecca Bio-Tech, customer satisfaction is our top priority. We offer excellent after-sales support, including:
Assistance with product applications
Technical support for formula design and production processes
Post-shipment follow-ups to ensure product quality
Solutions to any questions or issues regarding the product
For more information about our product or to place an order, feel free to contact us at information@sxrebecca.com. We look forward to helping you improve the health and vitality of your customers with our premium, natural products.
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