Synthetic Capsaicin Powder also named Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units).
Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling.
We provide a detailed Certificate of Analysis (COA) to ensure all batches meet stringent purity, stability, and regulatory requirements. The COA includes testing results for heavy metals, residual solvents, microbial content, and other critical parameters.
HPLC Chromatogram
|
Item |
Specification |
Results |
|
Appearance |
Off-white to white Powder |
White Powder |
|
Assay of Synthetic Capsaicin |
≥ 98%(HPLC) |
99.13% |
|
Decylic acid vanillylamide (N-VANILLYLDECANAMIDE) |
|
0.65% |
|
Vanillylamine hydrochloride (4-Hydroxy-3-methoxybenzylamine hydrochloride) |
|
0.14% |
|
Other similar alkalis |
|
0.08% |
|
Melting Range |
55～61℃ |
58-59℃ |
|
Loss on drying |
≤ 1.0% |
0.18% |
|
Heavy metal |
≤ 5 ppm |
0.0 |
|
Ignition residue |
≤ 1.0% |
0.17% |
|
Solubility |
Soluble in Chloroform, Ethanol & Insoluble in Water |
|
|
Conclusion |
Conforms with Company Standards |
|
Scoville designed a set of experimental methods called "Scoville Organoleptic test" to measure capsaicin content. This method is to dissolve one unit of capsaicin in the sugar water, and then give it to several people to taste, and then gradually increase the amount of sugar water until the spicy taste cannot be tasted. Scoville Hotness Units (SHU). For example, bell peppers have no spicy taste when eaten raw, so the SHU is 0~5; the SHU of allspice is between 100 and 500, which means that one unit of allspice requires 100~500 times of sugar water to neutralize. The substance with the highest SHU value is capsaicin, which
is around 15,000,000~16,000,000. Because this experimental method is greatly influenced by human subjectivity, later generations developed a method called "high performance liquid chromatography" (HPLC) to measure. However, because the Scoville indicator has been in use for a long time, the measurement value of high performance liquid chromatography is still often converted into SHU to represent the capsaicin content.
1. Medical field: It can be used for non-addictive analgesia, inhibit bacteria and fungi, and promote blood circulation. It can be made into ointments, tinctures, creams, patches, etc., for the treatment of arthritis, muscle pain, back pain, neuralgia left over from sports sprains and other diseases.
2. Rat-proof cable materials: synthetic capsaicin powder is used as a rodent-proof additive for cable plastic sheaths to prevent animals from chewing and cutting, and is widely used in the cable and optical cable industries.
3. Biological antifouling agent: used in ship antifouling paint, applied to the parts of ships and offshore buildings that come into contact with seawater to prevent the attachment of marine organisms such as algae, shellfish, and mollusks.
4. Repellent: using the strong tear-inducing and sneezing effect of synthetic capsaicin, it is used to manufacture tear gas and other repellent equipment and personal defense products.
5. Biological pesticides: It is the main ingredient in the production of new green and environmentally friendly biological pesticides, which have the characteristics of high efficacy, long-lasting effect, good safety, and no pollution to the environment against order pests.
6. Drug addiction treatment: Drug addiction treatment injections made of high-purity synthetic capsaicin have a strong drug addiction treatment effect on all drug addictions.
7. Local weight loss: Synthetic capsaicin Powder can improve fat metabolism, consume excess fat, control weight, and achieve weight loss. It is especially suitable for patients with local obesity.
8. Treatment of skin diseases: such as stubborn psoriasis, urticaria, eczema, neurodermatitis, pruritus, and pruritus caused by hemodialysis.
9. Lowering cholesterol: It can promote blood circulation, accelerate blood purification, and promptly remove various toxins from the blood by promoting vasodilation, thereby lowering cholesterol, controlling blood pressure, and preventing thrombosis. It has a good effect on the prevention and treatment of hypertension and cardiovascular and cerebrovascular diseases.
10. Military use:It can be used in the military to make tear gas, tear gas guns, and defensive weapons.
(1)It is in high purity and good quality with competitive price and wide usage.
(2)In industry, compared with the natural capsaicin, the product can lower the rawmaterial cost.
Our advanced testing facilities and strict quality control protocols ensure that every batch of Synthetic Capsaicin Powder meets international standards, including GMP, FDA, and other regulatory certifications.
We offer a range of packaging options to preserve the stability and quality of our product. Each package is sealed and labeled according to regulatory requirements, with clear handling and storage instructions. We partner with reputable logistics providers to ensure timely and safe delivery worldwide.
For first-time clients or custom orders, we offer sample shipments for testing and evaluation.
Our dedicated customer support team can help you answer questions about product specifications, applications and efficacy, as well as provide customized products or packaging. You can contact us at any time according to the email address.
Shaanxi Rebecca Bio-Tech Co.,LTD, specializes in Research&Production on plant extracts, isolation of active ingredients of traditional Chinese medicine and functional compound formulations of traditional Chinese medicine. We have a high-quality technical R&D team with strong technical force, many experienced R&D personnel, an excellent marketing team and domestic regional channel partners. We specialize in product market development and product after-sales service, and are committed to serving customers all over the world. We provide high-quality natural herbal extracts to customers in the pharmaceutical, health care products, beverages, cosmetics and other industries.
At Rebecca, we follow market development trends and actively develop innovative products on the premise of continuity and diversity of herbal medicines. We believe that natural specialty ingredients and innovative technologies are the best basis for us to meet our customers' needs. There are other related high-quality products under our main categories, and we also support customized services.
As a professional manufacturer of Chinese plant and herbal extracts, we firmly believe that natural, healthy and functional products are our unremitting pursuit of excellence.
We are looking forward to working with you!!!
Q: Is Synthetic Capsaicin Powder suitable for sensitive applications?
A: Yes, it is highly purified and tested to minimize side effects.
Q: Can I request a COA before purchase?
A: Absolutely, please contact us for the latest batch COA.
Q: What are the storage conditions?
A: Store in a cool, dry place away from direct sunlight.
Feel free to reach out to us at information@sxrebecca.com for more details. We look forward to serving your needs for high-quality, reliable Synthetic Capsaicin Powder.
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